The Murine Embryonic Stem Cell Core has been created to help you create mutations in murine embryonic stem cells. The core has several missions, including development of state-of-the-art reagents for the production of targeted mutations in embryonic stem cells, the creation of quality-controlled embryonic stem cell lines, and the teaching of methods for embryonic stem cell culture and manipulation. The core provides quality-controlled cells developed here at Washington University. In addition, our core can provide a teaching service, so that "hands-on" production of targeted ES clones can be learned. Finally, the core will attempt to assist all users with blastocyst injection, if injection services are not available to that laboratory. By providing a comprehensive service, we hope to facilitate the production of gain-of-function and loss-of-function mouse models for our faculty.
Important Information concerning murine C57BL6N substrains
PUBLICATION ACKNOWLEDGEMENT: If research supported by the Embryonic Stem Cell Core results in publication, please acknowledge this support by including the following in your publication(s):
We thank the Alvin J. Siteman Cancer Center at Washington University School of Medicine and Barnes-Jewish Hospital in St. Louis, Mo., for the use of the Embryonic Stem Cell Core, which provided __________ service. The Siteman Cancer Center is supported in part by an NCI Cancer Center Support Grant #P30 CA91842.
Murine Embryonic Stem Cell Core
The Alvin J. Siteman Cancer Center at Washington University
St. Louis, Missouri 63110
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