Cre Database
Last Updated: 09/04/2009
| Promoter | Specificity | Type of Recombinase | Efficiency | Mouse Strains | WUMS Contact Information | Originating Source / Investigator | References | Comments |
| AP2 | distal limb mesenchyme | cre (creface) | Good | C57BL/6 | Dr. David Ornitz | Dr. Trevor Williams | - | - |
| c Beta actin | ubiquitous | creER | Mosaic | Mixed | Dr. Raphael Kopan Dr. Joshua Sanes | Dr. Corrinne Lobe | Guo, C., et al (2002) Genesis 32, 8-18 | MTA required / local colony |
| CD19 | B cells | cre | Good | C57BL/6 | Dr. Skip Virgin | Jackson Laboratories | unpublished | - |
| Cfes | hematopoietic stem cells partial endothelial cells | cre | - | C57BL/6 N10 founder B6CBA F1 | Dr. Monica Bessler | Dr. Pier Paolo Pandolfi | Keller et al, (2001) J. of Experimental Medicine 104, number 5, 581-589 | - |
| Col 1 | osteoblasts | cre | Good | C57BL/6 | Dr. David Ornitz | Dr. Gerard Karsenty | Dacquin, R., et al, (2002) Developmental Dynamics 224, no. 2, 245 - 251 | - |
| Col 1 | osteoblasts | creERT | Good | C57BL/6 | Dr. David Ornitz | Dr. Tatsuya Kobayashi Dr. Hank Kronenberg | unpublished | - |
| Col 2 | proliferating chondrocytes | cre | Fair | C57BL/6 | Dr. David Ornitz | Dr. Dmitry Ovchinnikov Dr. Richard Behringer | Ovchinnikov, D., et al, (2000) Genesis 26, 145 - 146 | - |
| Col X (collagen 10) | hypertrophic chondrocytes | cre | Good | C57BL/6 | Dr. David Ornitz | Dr. Kathryn S.E. Cheah | unpublished | - |
| Dermo 1 | mesencyhmal condensations dermis | cre | High | C57BL/6 | Dr. David Ornitz | - | Yu, K., et al (2003) Development 130, 3063 - 3074 | - |
| EIIa | embryo proper (E2 - E4.5) | cre | - | C57BL/6 N10 > founder FVB/NJ | Dr. Monica Bessler | Dr. Heiner Westphal (NIH) | Tremml, G., et al, (1999) The American Society of Hematology, 2945-2954 | MTA required / local colony |
| Engrailed | mid & hind brain | cre | - | FVB/N | Dr. David Ornitz | Dr. Alex Joyner | Zinyk, D.L., et al (1998) Current Biology May 21, 8, no. 11, 665 - 668 | - |
| GATA-1 | erythrocytes megakaryocytes | cre | - | C57BL/6 N6 > founder CD-1 | Dr. Monica Bessler | Dr. Stuart Orkin | Jasinski, M., et al, (2001) The American Society of Hematology, 2248-2255 | - |
| K14 | basal keratinocytes | creER | High | mixed | Dr. Raphael Kopan | Dr. Elain Fuchs (Rockefeller Institute) | Vasioukhin, V., et al (1999) PNAS 96, 8551-8556 | MTA required / local colony |
| Lysozyme M | Macrophages | cre | Good | C57BL/6 | Dr. Skip Virgin | Jackson Laboratories | unpublished | - |
| Lck | T-cells | cre | Good | C57BL/6 | Dr. Skip Virgin | Taconic | unpublished | - |
| Lckcre | Thymocytes | cre | - | - | Dr. Helen Piwnica-Worms | Jackson Laboratories, #003802 Dr. Jamey Marth, UCSD | Hennet, T et al (1995) PNAS 92:12070-4 | - |
| MLC 2 | cardiac muscle | 2v cre | OK | C57BL/6 | Dr. David Ornitz | Dr. K.R. Chien | Minamisawa, S., et al (1999) J. of Biological Chemistry 274, no. 15, 10066 - 10070 | - |
| Msx2 (439 bp) | apical ectodermal ridge skin, hair | cre | Mosaic | mixed | Dr. Raphael Kopan | Dr. Gail Martin (UCSF) | Sun, X., et al (2000) Nature Genetics 25, 83-86 | MTA required / local colony |
| Mx1 | - | cre | - | C57BL/6J N6 | Dr. Monica Bessler | Jackson Laboratory | - | - |
| Nestin | neuroblasts | cre | - | C57BL/6J | Dr. David Ornitz | Jackson Laboratory | - | - |
| Osteocalcin | mature osteoblasts | cre | Fair | C57BL/6 | Dr. David Ornitz | Dr. Gerard Karsenty | Dacquin, R., et al, (2002) Developmental Dynamics 224, no. 2, 245 - 251 | - |
| PLP | preliminary results nervous system oligodendrocytes Schwann cells | cre | - | - | Dr. John Russell | - | - | - |
| Rosa26 | ubiquitous | creER | - | C57BL/6 N3 | Dr. Monica Bessler Dr. David Ornitz | Dr. Marc Vooijs (Kopan lab) Dr. Anton Berns (NKI) | Vooijs, M., et al, (2001) EMBO Rep 2, 292-297. | - |
| Rosa26 | ubiquitous | creERT | High | mixed | Dr. Raphael Kopan | Dr. Marc Vooijs (Kopan lab) Dr. Anton Berns (NKI) | Vooijs, M., et al (2001) EMBO 21, 292-297 | MTA required / local colony |
| RosacreER | Ubiquitous | creER | - | - | Dr. Helen Piwnica-Worms | Dr. Anton Berns (NKI) Netherlands Cancer Center Amsterdam, Netherlands | Vooijs, M., et al (2001) EMBO Rep. 2(4):292-7 | Needs 4-hydroxytamoxifen to induce. |
| Tie-1 | endothelial cells | cre | Good | C57BL/6 N5 > | Dr. Monica Bessler Dr. David Ornitz | Dr. Reinhard Fassler Dr. Erika Gustafsson | Gustafsson, E., et al, (2001) J. Cell Science 114, 671-676. | - |
| Villin | intestine | cre | Good | C57BL/6 | Dr. Skip Virgin virgin@wustl.edu | Dr. Deborah L Gumucio | Madison BB et al, (2002) J. Biol. Chem. 277, number 36, 33275-83 | - |
| VillincreERT | intestines | creERT2 | mosaic | - | Dr. Helen Piwnica-Worms | Dr. Sylvie Robine Institut Curie Paris, France | el Marjou, F et al (2004) Genesis 39(3):186-93 | - |
| Wapcre | secretory epithelium of the mammary gland | cre | - | - | Dr. Helen Piwnica-Worms | NCI Repository Dr. Lothar Hennighausen | Wagner, KU et al 1997 Nucleic Acids 25:4323-30 | - |