The Washington University Mouse Embryonic Stem Cell (ESC) Core is a service generously supported by the Departments of Medicine, Developmental Biology, Cell Biology, Ophthalmology, Orthopedic Surgery, Anesthesiology and Neurology. The mission of the ESC Core is to help you create mutations in murine embryonic stem cells. The core has several aspects to this mission, including development of state-of-the-art reagents for the production of targeted mutations in embryonic stem cells, the creation of quality-controlled embryonic stem cell lines, and the teaching of methods for embryonic stem cell culture and manipulation. By providing a comprehensive service, we hope to facilitate the production of gain-of-function and loss-of-function mouse models for our faculty.

The core will be accepting non-WUSM work, and has a price structure that allows other institutions, non-profits and commercial interests to be able to participate. These charges are detailed on the Services page.

Transfected Cell Line Performance Data

(1997 to present)

Publication Information

As of April 7, 2008, the NIH requires investigators with a publication using any NIH-funded shared resources to submit (or have submitted for them) their final, peer reviewed manuscripts to PubMed Central(PMC) upon acceptance of publication, to be made publicly available within 12 months of publication. Many journals automatically submit these for authors, but Washington University also has assistance available through the Becker Medical Library. Please see http://publicaccess.nih.gov/FAQ.htm#b7 or http://becker.wustl.edu/services/scholarly/nihpolicy.html for more information.

PUBLICATION ACKNOWLEDGEMENT: If research supported by the Embryonic Stem Cell Core results in publication, please acknowledge this support by including the following in your publication(s):

We thank the Washington University at St. Louis for the use of the Embryonic Stem Cell Core, which provided __________ service.

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Site Updated: March 28, 2015